GO TOP

Field

Molecular and Chemical Life Science :
Molecular and Network Genomics

Research

Professor HIGASHITANI Atsushi
Campus Katahira campus
Laboratory Molecular Genetics and Physiology
Tel +81-22-217-5715
E-mail atsushi.higashitani.e7@tohoku.ac.jp
Website https://www.lifesci.tohoku.ac.jp/research/fields/laboratory.html?id=2550 https://www.lifesci.tohoku.ac.jp/en/research/fields/laboratory.html?id=2550
Career
Mar. 1990 Assistant Professor, Department of Microbial Genetics, National Institute of Genetics, Japan
Mar. 1997 Associate Professor, Institute of Genetic Ecology, Tohoku University
Apr.2001 Professor, Graduate School of Life Sciences, Tohoku University
Selected Publications
Recent major papers
  1. Wu X, Seida M, Abe T, Higashitani A. Mitochonic acid 5 attenuates age-related neuromuscular dysfunction associated with mitochondrial Ca2+ overload in Caenorhabditis elegans. NPJ Aging. 2023 9:20.
  2. Fuentes-Merlos MI, Bamba M, Sato S, Higashitani A. Self-grafting-induced epigenetic changes leading to drought stress tolerance in tomato plants. DNA Research 2023 30:dsad016.
  3. Şekerci K, Higashitani N, Ozgur R, Uzilday B, Higashitani A, Turkan I. A stratagem for primary root elongation under moderate salt stress in the halophyte Schrenkiella parvula. Physiologia Plantrum 2023 175:e13937.
  4. Higashitani A, Teranishi M, Nakagawa Y, Itoh Y, Sudevan S, Szewczyk NJ, Kubota Y, Abe T, Kobayashi T. Increased mitochondrial Ca2+ contributes to health decline with age and Duchene muscular dystrophy in C. elegans. FASEB Journal 2023 37:e22851
  5. Deane CS, Phillips BE, Willis CRG, Wilkinson DJ, Smith K, Higashitani N, Williams JP, Szewczyk NJ, Atherton PJ, Higashitani A, Etheridge T. Proteomic features of skeletal muscle adaptation to resistance exercise training as a function of age. Geroscience 2023 45:1271-87.
  6. Sudevan S, Muto K, Higashitani N, Hashizume T, Higashibata A, Ellwood RA, Deane CS, Rahman M, Vanapalli SA, Etheridge T, Szewczyk NJ, Higashitani A. Loss of physical contact in space alters the dopamine system in C. elegans. iScience 2022 25:103762.
  7. Higashitani A, Hashizume T, Takiura M, Higashitani N, Teranishi M, Oshima R, Yano S, Kuriyama K, Higashibata A. Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans. NPJ Microgravity 2021 7:33.
  8. Dündar G, Shao Z, Higashitani N, Kikuta M, Izumi M, Higashitani A. Autophagy mitigates high-temperature injury in pollen development of Arabidopsis thaliana. Developmental Biology 2019 456:190-200.
  9. Sakata T, Oda S, Tsunaga Y, Shomura H, Kawagishi-Kobayashi M, Aya K, Saeki K, Endo T, Nagano K, Kojima M, Sakakibara H, Watanabe M, Matsuoka M, Higashitani A. Reduction of gibberellin by low temperature disrupts pollen development in rice. Plant Physiology 2014 164:2011-9.
  10. Sakata T, Oshino T, Miura S, Tomabechi M, Tsunaga Y, Higashitani N, Miyazawa Y, Takahashi H, Watanabe M, Higashitani A. Auxins reverse plant male sterility caused by high temperatures. Proceeding National Academy of Science U.S.A. 2010 107:8569-74.
Activities in Academic Societies

The Japanese Society for Biological Sciences in Space, The Japanese Society of Mitochondrial Research and Medicine, Japan Muscle Society

Teaching
General Molecular and Chemical Life Sciences, Advanced Molecular and Chemical Life Sciences II (Molecular and Network Genomics) , Joint Lecture of Ecology

Recent Activities

The research includes studies of muscle atrophy and nerve damage associated with ageing and disease, and space experiments, using the nematode worm as one of the model organisms.

Message to Students

Please enjoy your scientific research.