GO TOP

Field

Molecular and Chemical Life Science :
Multilevel Biomolecular Structure and Dynamics

Research

JAPANESE
Associate Professor KOWADA Toshiyuki
Campus Katahira campus
Laboratory Biofunctional Chemistry and Nanobiotechnology
Tel +81-22-217-5118
E-mail toshiyuki.kowada.d5＠tohoku.ac.jp
Website http://www2.tagen.tohoku.ac.jp/lab/mizukami/
Career
2005              BS, Division of Industrial Chemistry, Faculty of Engineering, Kyoto University
2010              PhD, Graduate School of Engineering, Kyoto University
2010–2011    Specially appointed researcher, WPI-Immunology Frontier Research Center (IFReC), Osaka University
2011–2014    Specially appointed assistant professor, WPI-Immunology Frontier Research Center (IFReC), Osaka University
2014–2016    Postdoctoral Fellow, Stanford University, USA
Nov. 2016–    Assistant professor, Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University
Selected Publications
＜Papers＞
  1. “Real-time intravital imaging of pH variation associated with osteoclast activity” Hiroki Maeda, Toshiyuki Kowada, Junichi Kikuta, Masayuki Furuya, Mai Shirazaki, Shin Mizukami,Masaru Ishii, Kazuya Kikuchi, Nat. Chem. Biol. 2016, 12, 579–585.
  2. “BODIPY-based probes for the fluorescence imaging of biomolecules in living cells” Toshiyuki Kowada, Hiroki Maeda, Kazuya Kikuchi, Chem. Soc. Rev. 2015, 44, 4953–4972.
  3.  “Dynamic visualization of RANKL and Th17-mediated osteoclast function”Junichi Kikuta, Yoh Wada, Toshiyuki Kowada, Ze Wang, Ge-Hong Sun-Wada, Issei Nishiyama,Shin Mizukami, Nobuhiko Maiya, Hisataka Yasuda, Atsushi Kumanogoh, Kazuya Kikuchi,Ronald N. Germain, Masaru Ishii, J. Clin. Invest. 2013, 123, 866–873.
  4. “In Vivo Fluorescence Imaging of Bone-Resorbing Osteoclasts”Toshiyuki Kowada, Junichi Kikuta, Atsuko Kubo, Masaru Ishii, Hiroki Maeda, Shin Mizukami, Kazuya Kikuchi, J. Am. Chem. Soc. 2011, 133, 17772–17776.
  5. “Near-infrared BODIPY dyes modulated with spirofluorene moieties”Toshiyuki Kowada, Shuhei Yamaguchi, Hiroki Fujinaga, Kouichi Ohe  Tetrahedron 2011, 67, 3105–3110.
  6.  “Highly Fluorescent BODIPY Dyes Modulated with Spirofluorene Moieties” Toshiyuki Kowada, Shuhei Yamaguchi, Kouichi Ohe, Org. Lett. 2010, 12, 296–299.
 
＜Books＞
  1. Optical Probes in Biology, CRC Press, 2015, edited by Jin Zhang, Sohum Mehta, Carsten Schultz. “Chemical probes for fluorescence imaging in living mice” Chapter 13, 335–354, 2015. Toshiyuki Kowada, Hiroki Maeda, Kazuya Kikuchi.
Activities in Academic Societies
Chemical Society of Japan, Division of Biofunctional Chemistry, The Chemical Society of Japan, Japanese Society for Chemical Biology, The Society of Synthetic Organic Chemistry, Japan Bioimaging Society

Research