Department of Developmental Biology and Neurosciences
Division of Neuroscience

Laboratory of Neuroethology

p_tanimoto
Hiromu Tanimoto
Campus Katahira Campus
Research field Neuroethology
Telephone 022-217-6223
E-mail hiromutatm.tohoku.ac.jp

Google scholar
https://scholar.google.co.jp/citations?user=RYlXq48AAAAJ&hl=en

The Laboratory of Neuroethology is a new laboratory transferred from the Max Planck Institute in Germany. If you are interested in joining our lab, I encourage you to contact us.

Career
1997 BSc: Department of Chemistry, Tokyo Metropolitan University. Supervised by Dr. H. Kaji and Prof. T. Isobe.
1999 MSc: Department of Biochemistry and Biophysics, Institute of Molecular and Cellular Biosciences, University of Tokyo. Supervised by Prof. T. Tabata.
2002 PhD: Department of Biochemistry and Biophysics, Institute of Molecular and Cellular Biosciences, University of Tokyo. Supervised by Prof. T. Tabata.

2002-2006

Postdoc: Department of Genetics and Neurobiology, University of Wuerzburg . Supervised by Prof. M. Heisenberg.
2006-2007 Group Leader of Emmy-Noether Programme (DFG) at Department of Genetics and Neurobiology, University of Wuerzburg
2008-2013 Max-Planck Research Group Leader at the Max-Planck Institute of Neurobiology
Selected Publications

2016

Rohwedder A, Wenz NL, Stehle B, Huser A, Yamagata N, Zlatic M, Truman JW, Tanimoto H, Saumweber T, Gerber B, Thum AS. (2016) Four Individually Identified Paired Dopamine Neurons Signal Reward in Larval Drosophila. Curr Biol. pii: S0960-9822(16)00062-2.
DOI: 10.1016/j.cub.2016.01.012.

Thoma V, Knapek S, Arai S, Hartl M, Kohsaka H, Sirigrivatanawong P, Abe A, Hashimoto K, Tanimoto H. (2016) Functional dissociation in sweet taste receptor neurons between and within taste organs of Drosophila. Nat Commun 7:10678.
DOI: 10.1038/ncomms10678.

2015

Ichinose T, Aso Y, Yamagata N, Abe A, Rubin GM, Tanimoto H. (2015) Reward signal in a recurrent circuit drives appetitive long-term memory formation. Elife 4:e10719. 
DOI: http://dx.doi.org/10.7554/eLife.10719

Nehrkorn J, Tanimoto H, Herz AV, Yarali A. (2015) A model for non-monotonic intensity coding. R Soc Open Sci. 2(5):150120.
DOI:10.1098/rsos.150120.

Vogt K, Yarali A, Tanimoto H. (2015) Reversing stimulus timing in visual conditioning leads to memories with opposite valence in Drosophia. PLoS One, 10(10):e0139797.
DOI: 10.1371/journal.pone.0139797.

Appel M, Scholz CJ, Müller T, Dittrich M, König C, Bockstaller M, Oguz T, Khalili A, Antwi-Adjei E, Shauer T, Margulies C, Tanimoto H, Yarali A. Genome-Wide Association Analyses Point to Candidate Genes for Eletric Shock Avoidance in Drosophila melanogaster. PLoS One, 2015, 18:10(5):e0126986.
doi: 10.1371/journal.pone.0126986.

Yamagata N, Ichinose T, Aso Y, Plaçais PY, Friedrich AB, Sima R, Preat T, Rubin GM, Tanimoto H. Distinct dopamine neurons mediate reward signals for short- and long-term memories. Proc Natl Acad Sci U S A. 2015. 112(2): 578-83.
http://www.pnas.org/content/112/2/578.full 

2014

Aso Y, Sitaraman D, Ichinose T, Kaun K, Vogt K, Belliart-Guérin G, Plaçais PY, Robie A, Yamagata N, Schnaitmann C, Rowell W, Johnston R, Ngo T, Chen N, Korff W, Nitabach M, Heberlein U, Preat T, Branson K, Tanimoto H, Rubin G. (2014) Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila. eLife 3:e04580.
http://dx.doi.org/10.7554/eLife.04580

Aso Y, Hattori D, Yu Y, Johnston R, Iyer N, Ngo T, Dionne H, Abbott L, Axel R, Tanimoto H, Rubin G. (2014) The neuronal architecture of the mushroom body provides a logic for associative learning.eLife 3:e04580.
http://dx.doi.org/10.7554/eLife.04577

Vogt K, Schnaitmann C, Dylla K, Knapek S, Aso Y, Rubin GM, Tanimoto H (2014).Shared mushroom body circuits operate visual and olfactory memories in Drosophila. eLife DOI: http://dx.doi.org/10.7554/eLife 3:e02395.
http://elifesciences.org/content/3/e02395

Galili DS, Dylla KV,  Lüdke A, Friedrich AB,  Yamagata  N, Wong JY, Ho CH, Szyszka P, Tanimoto H. (2014). Converging circuits for temperature and shock mediate aversive olfactory conditioning in Drosophila. Curr Biol 24: 1712-22
http://www.cell.com/current-biology/abstract/S0960-9822(14)00779-9

2013

Schnaitmann C, Garbers C, Wachtler T, Tanimoto H.(2013) Color discrimination with broadband photoreceptors. Curr Biol 23:2375-8214.
http://www.sciencedirect.com/science/article/pii/S0960982213013122

Plaçais PY, Trannoy S, Friedrich AB, Tanimoto H, Preat T. (2013)Two pairs of mushroom body efferent neurons are required for appetitive long-term memory retrieval in Drosophila. Cell Rep 5:769-80
http://www.cell.com/cell-reports/abstract/S2211-1247(13)00555-X

Dylla K, Galili DS, Szyszka P, Luedke (2013). A Trace conditioning in insects - Keep the trace! Fron Physiol, doi: 10.3389
http://www.frontiersin.org/invertebrate_physiology/10.3389/fphys.2013.00067/abstract

Knapek S, Kahsai L, Winther AM, Tanimoto H, Nässel DR (2013). Short neuropeptide F acts as a functional neuromodulator for olfactory memory in Kenyon cells of Drosophila mushroom bodies. J Neurosci 33: 5340-5.35
http://www.jneurosci.org/content/33/12/5340.long

Gruber F, Knapek S, Fujita M, Matsuo K, Bräcker L, Shinzato N, Siwanowicz I, Tanimura T, Tanimoto H (2013). Suppression of conditioned odor approach by feeding is independent of taste and nutritional values in Drosophila. Curr Biol 23: 507-14
http://www.cell.com/current-biology/retrieve/pii/S0960982213001516

 

2012

Ueno T, Tomita J, Tanimoto H, Endo K, Ito K, Kume S, Kume K (2012). Identification of a dopamine pathway that regulates sleep and arousal in Drosophila. Nat Neurosci 15: 1516–1523
http://dx.doi.org/10.1038/nn.3238

Liu C, Placais PY, Yamagata N, Pfeiffer BD, Aso Y, Friedrich AB, Siwanowicz I, Rubin GM, Preat T, Tanimoto H (2012). A subset of dopamine neurons signals reward for odour memory in Drosophila. Nature 488: 512-6
http://www.nature.com/nature/journal/v488/n7412/full/nature11304.html

Aso Y, Herb A, Ogueta M, Siwanowicz I, Friedrich AB, Templier T, Ito K, Scholz H, Tanimoto H (2012). Three dopamine pathways induce aversive odor memories with different stability. PLoS Genetics 8:e1002768
 http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1002768

Yarali A, Nehrkorn J, Tanimoto H, Herz AVM (2012). Event timing in associative learning: From biochemical reaction dynamics to behavioural observations. PLoS One 7:e32885 
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0032885

Plaçais PY, Trannoy S, Isabel G, Aso Y, Siwanowicz I, Belliart-Guérin G, Vernier P, Birman S, Tanimoto H, Preat T (2012). Slow oscillations in two pairs of dopaminergic neurons gate long-term memory formation in Drosophila. Nature Neurosci 15: 592-9
http://www.nature.com/neuro/journal/v15/n4/full/nn.3055.html

Butcher NJ, Friedrich AB, Lu Z, Tanimoto H, Meinertzhagen IA (2012). Different classes of input and output neurons reveal new features in microglomeruli of the adult Drosophila mushroom body calyx. J Comp Neurol 520: 2185-201
http://onlinelibrary.wiley.com/doi/10.1002/cne.23037/abstract

 

2011

Tomita J, Mitsuyoshi M, Ueno T, Aso Y, Tanimoto H, Nakai Y, Aigaki T, Kume S, Kume K (2011). Pan-neuronal knockdown of calcineurin reduces sleep in the fruit fly Drosophila. J Neurosci 31: 13137-13146
http://www.jneurosci.org/cgi/content/abstract/31/37/13137

Eschbach C, Vogt K, Schmuker M, Gerber B (2011). The Similarity between Odors and Their Binary Mixtures in Drosophila. Chem Senses, epub doi: 10.1093/chemse/bjr016

Séjourné J, Plaçais PY, Aso Y, Siwanowicz I, Trannoy S, Thoma V, Tedjakumala SR, Rubin GM, Tchénio P, Ito K, Isabel G, Tanimoto H, Préat T (2011). Mushroom Body Efferent Neurons Responsible For  Aversive Olfactory Memory Retrieval In Drosophila. Nature Neurosci 14: 903-10
http://www.nature.com/neuro/journal/v14/n7/abs/nn.2846.html

Galili DS, Lüdke A, Galizia CG, Szyszka P, Tanimoto H (2011). Olfactory trace conditioning in Drosophila. J Neurosci 31: 7240-7248
http://www.jneurosci.org/content/31/20/7240.full

Michels B, Chen YC, Saumweber T, Mishra D, Tanimoto H, Schmid B, Engman O, Gerber B (2011). Cellular Site and Molecular Mode of Synapsin Action in Associative Learning. Learn Mem 18: 332-44
http://learnmem.cshlp.org/content/18/5/332.full

Knapek S, Sigrist SJ, Tanimoto H (2011). Bruchpilot, a synaptic active zone protein for anesthesia-resistant memory. J Neurosci 31: 3453-3458
http://www.jneurosci.org/content/31/9/3453.abstract

 

2010

Yarali A, Gerber B (2010). A neurogenetic dissociation between punishment-, reward- and relief learning in Drosophila. Front Behav Neurosci 4: 189
http://www.frontiersin.org/Behavioral_Neuroscience/10.3389/fnbeh.2010.00189/abstract

Aso Y, Siwanowicz I, Bräcker L, Ito K, Kitamoto T, Tanimoto H (2010). Specific Dopaminergic Neurons for the Formation of Labile Aversive Memory. Curr Biol 20: 1445-1451
http://dx.doi.org/10.1016/j.cub.2010.06.048

Andreatta M, Muehlberger A, Yarali A, Gerber B, Pauli P (2010). A rift between implicit and explicit condituined valence in human pain relief learning. Proc Biol Sci 277: 2411-2416
http://rspb.royalsocietypublishing.org/content/277/1692/2411.long

Schnaitmann C, Vogt K, Triphan T, Tanimoto H (2010). Appetitive and aversive visual learning in freely moving Drosophila. Front Behav Neurosci 4: 10
http://dx.doi.org/10.3389/fnbeh.2010.00010

Busch S, Tanimoto H (2010). Cellular  configuration of single octopamine neurons in Drosophila. J Comp Neurol 518: 2355-2364
http://dx.doi.org/10.1002/cne.22337

Knapek S, Gerber B, Tanimoto H (2010). Synapsin is selectively required for anesthesia-sensitive memory. Learn Mem 17: 76-79
http://www.learnmem.org/cgi/pmidlookup?view=long&pmid=20154352

 

2009

Busch S, Selcho M, Ito K, Tanimoto H (2009). A map of octopaminergic neurons in the Drosophila brain. J Comp Neurol 513: 643-667
http://dx.doi.org/10.1002/cne.21966

Aso Y, Grübel K, Busch S, Friedrich AB, Siwanowicz I, Tanimoto H (2009). The mushroom body of adult Drosophila characterized by GAL4 drivers. J Neurogenet 23: 156-172
http://informahealthcare.com/doi/abs/10.1080/01677060802471718

Tanimoto H (2009). Genetic analysis of the neuronal circuit underlying olfactory memory in Drosophila [Japanese]. Molecular Entomology - Insect science in the postgenomic era. Tokyo, Japan: Kyoritsu Shuppan

 

2008

Yarali A, Niewalda T, Chen Y C, Tanimoto H, Duerrnagel S, Gerber B (2008). Pain relief learning in fruit flies. Anim Behav 76(4): 1173-1185
http://linkinghub.elsevier.com/retrieve/pii/S000334720800273X

Tanaka NK, Tanimoto H, Ito K (2008) Neuronal assemblies of the Drosophila mushroom body. J Comp Neurol 508: 711-755
http://dx.doi.org/10.1002/cne.21692

 

2007

Tanimoto H, Suzuki T (2007). Meeting report: JDRC 8: History, Neurobiology and Imaging. Fly 1: 291-293
http://www.landesbioscience.com/journals/fly/abstract.php?id=5242

Thum AS, Jenett A, Ito K, Heisenberg M, Tanimoto H (2007). Multiple memory traces for olfactory reward learning in Drosophila. J Neurosci 27: 11132-11138
http://www.jneurosci.org/cgi/pmidlookup?view=long&pmid=17928455

Suh GS, Ben-Tabou de Leon S, Tanimoto H, Fiala A, Benzer S, Anderson DJ (2007). Light activation of an innate olfactory avoidance response in Drosophila. Current Biol 17: 905-908
http://linkinghub.elsevier.com/retrieve/pii/S0960-9822(07)01324-3

Teaching

Advanced Lecture on Developmental Biology and Neurosciences, Advanced Cell Biology I, Advanced Lecture on Neuroethology

Recent Activities

Refer to the papers listed above for details of our recent progress.

Message to Students

Inquiries and applications for positions at all levels (e.g. internship, part-time lab managers/technicians, graduate students, and postdocs) are welcome at any time.  As we are always exploring diverse research directions, your background does not necessarily match our research focus.  Availability of financial support is however not always guaranteed; you are encouraged to seek your own funding.