|専攻分野||Biophysics, single-molecule spectroscopy|
I have liked to build new apparatuses since I was a student. Even now I am developing a device for detecting single molecules using a combination of the optical measurement and the automated data analysis.
Graduated from Department of Physics, Tokyo
Institute of Technology; completed master’s course, Department of Physics, Graduate
School of Science and Engineering, Tokyo Institute of Technology.
Hiroyuki Oikawa, Kiyoto Kamagata ,Munehito Arai, and Satoshi Takahashi “Complexity of the Folding Transition of the B domain of Protein A Revealed by the High-Speed Tracking of Single-Molecule Fluorescence Time Series” J. Phys. Chem. B, 119, 6081-6091 (2015)
Hiroyuki Oikawa, Yuta Suzuki, Masataka Saito, Kiyoto Kamagata, Munehiro Arai, and Satoshi Takahashi “Microsecond dynamics of an unfolded protein by a line confocal tracking of single molecule fluorescence” Sci. Rep. 3, 2151, (2013)
Daisuke Uchiyama, Hiroyuki Oikawa, Kohei Otomo, Mamoru Nango, Takehisa Dewa, Satoru Fujiyoshi, and Michio Matsushita “Reconstitution of bacterial photosynthetic unit in a lipid bilayer studied by single-molecule spectroscopy at 5 K”, Phys. Chem. Chem. Phys., 13, 11615-11619 (2011)
Hiroyuki Oikawa, Satoru Fujiyoshi, Takehisa Dewa, Mamoru Nango, and Michio Matsushita “How Deep Is the Potential Well Confining a Protein in a Specific Conformation? A Single-Molecule Study on Temperature Dependence of Conformational Change between 5 and 18 K. “ J. Am. Chem. Soc., 130, 4580-4581. (2008)
The Biophysical Society of Japan, Protein Science Society of Japan, Japan Society for Molecular Science
Microsecond-resolved tracking of single-molecule dynamics of protein folding.
Let us observe an individual character of each single biomolecule using the unique methods.