Department of Biomolecular Sciences
Division of Biomolecular Chemistry

Analytical Bioorganic Chemistry 分野

1-5itto
Kaori Itto
キャンパス Katahira キャンパス
専攻分野 Organic Chemistry
連絡先 022-217-6203
E-mail itto.katbiochem.tohoku.ac.jp
ホームページ http://www.agri.tohoku.ac.jp/bunseki/index-j.html
経歴

Tohoku Pharmaceutical Univ: B.S. 2008.
Tohoku Univ. Grad. Sch. of Life Sciences: Ph.D. 2014
(Research training as visiting graduate student: Uppsala Univ. Prof. P. G. Andersson group, 2009)
Assistant Professor, Tohoku Univ. Grad. Sch. of Life Science (2014-)

著書・論文

[1] Alexander Paptchikhine, Kaori Itto, Pher. G. Andersson
Sequential Birch reaction and asymmetric Ir-catalyzed hydrogenation as a route to chiral building blocks
Chemical Communications, 2011, 47, 3989–3991.

[2] Yusuke Miyake, Xiaolei Wang, Mitsuo Amasaka, Kaori Itto, Shu Xu, Hirokazu Arimoto, Hirotada Fujii, Hiroshi Hirata
Simultaneous Imaging of an Enantiomer Pair by Electron Paramagnetic Resonance Using Isotopic Nitrogen Labeling
Analytical Chemistry, 2013, 85, 985-990.

[3] Xu Shu*, Kaori Itto*, Masahide Satoh, Hirokazu Arimoto
(* These authors contributed equally to this work and are co-first authors.)
Unexpected dehomologation of primary alcohols to one-carbon shorter carboxylic acids using o-iodoxybenzoic acid (IBX)
Chemical Communications, 2014, 50, 2758–2761.

[4] Xiaolei Wang, Miho Emoto, Atsushi Sugimoto, Yusuke Miyake, Kaori Itto, Mitsuo Amasaka, Shu Xu, Hiroshi Hirata, Hirotada Fuji, Hirokazu Arimoto
Synthesis of 15N-labeled 4-oxo-2,2,6,6-tetraethylpiperidine nitroxide for EPR brain imaging
Tetrahedron Letters, 2014, 55, 2146-2149.

所属学会 The Chemical Society of Japan
担当講義 Laboratory experiment (Organic Synthesis I, Faculty of Agriculture)

最近の研究について

I obtained my Ph.D. degree in the field of Synthetic Organic Chemistry (Total synthesis of natural products, synthetic methodology) from this institution. In my research, I am now paying more attention to the functions of synthesized molecules such as antibacterial activity. For example, I am investigating the binding modes of glycopeptide antibiotics with their target protein using NMR spectroscopy. I believe this will lead to the rational development of new clinically useful antibacterial agents. Another project involves in vivo imaging of animals with EPR spectroscopy.

メッセージ

Our graduate school encompasses both chemistry and biology. Biological methods and concepts have been stimulating my imagination recently. In the Arimoto group, students with different backgrounds work together to solve important questions in chemical biology. I would like to welcome those of you interested in multidisciplinary research.