Department of Biomolecular Sciences
Division of Molecular Biosystems

Molecular Cell Biology 分野

p_nagai
Tomoaki Nagai
キャンパス Aobayama キャンパス
専攻分野 Laboratory of Molecular Cell Biology
連絡先 Tel:+81-22-795-6679
E-mail tnagaiatbiology.tohoku.ac.jp
ホームページ http://www.biology.tohoku.ac.jp/lab-www/mizuno_lab/
経歴
2008 B.Sc., Department of Biology, Faculty of Science, Tohoku University
2010 M.Sc., Graduate School of Life Sciences, Tohoku University
2011 - 2012 JSPS Research Fellowships for Young Scientists (DC2)
2013 Ph.D., Graduate School of Life Sciences, Tohoku University
2013 - 2014 Research Assistant in Tohoku University
2014 - present Assistant Professor in Tohoku University
著書・論文


(1) Nagai T., Ikeda M., Chiba S., Kannno S. I., Mizuno K.
Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase.  J. Cell. Sci. 126, 4369-4380 (2013).
(2) Kiuchi T., Nagai T., Ohashi K., Mizuno K.
Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.  J. Cell. Biol. 193. 365-380 (2011)

(1) Nagai T., Mizuno K. Multifaceted roles of Furry proteins in invertebrates and vertebrates. J. Biochem. 155, 137-146 (2014)
(2) Kiuchi T., Nagai T., Ohashi K., Watanabe N., Mizuno K.
Live-cell imaging of G-actin dynamics using sequential FDAP. Bioarchitecture 1, 240-244 (2011)

所属学会

The Molecular Biology Society of Japan
The Japanese Biochemical Society
Japan Society for Cell Biology
American Society for Cell Biology

最近の研究について

Primary cilia are antenna-like sensory organelles that emanate from the mother centrioles in quiescent vertebrate cells. Proper formation and function of primary cilia are essential for the development and homeostasis of many organ systems in vertebrates. Our research aim is to understand how primary cilium formation is regulated by using cell biological and biochemical approaches.