In graduate school, we worked on the elucidation of epigenetic mechanisms for the regulation of gene expression in budding yeast. Currently, I am attracted to study of the germ cells responsible for intergenerational information inheritance. I am interested in how the information possessed by germ cells is changed or inherited through dynamic phenomena such as germ-cell differentiation, fertilization, and ontogeny.
The Molecular Biology Society of Japan
In normal development, pluripotent stem cells differentiate into epiblasts, which have limited pluripotency, prior to the differentiation of germ-cells. Therefore, pluripotent stem cells do not directly acquire the nature of germ cells in vivo. Attempts to convert pluripotent stem cells directly into germ cells in vitro are expected to contribute not only to the artificial preparation of germ cells, but also to the understanding of the biological significance of germ-cell differentiation through epiblasts in vivo.
I think the best part of research is the course of setting up a problem on your own, formulating a hypothesis, and solving the problem with logic, experiments, and discussions. It becomes addictive to discover the laws of nature by repeating this process. Please nurture the seeds of your curiosity and grow buds of discovery. Let's grow them together if there is a chance for you to research with me.