Department of Environmental Life Sciences
Endowed Chairs

Microbial evolution and function research 分野

3-2nagata
Yuji Nagata
キャンパス Katahira キャンパス
専攻分野 Molecular microbiology, Bacterial genetics, Bacterial genomics, Biochemistry, and Protein engineering
連絡先 +81-22-217-5682
E-mail aynagaatige.tohoku.ac.jp
ホームページ http://www.ige.tohoku.ac.jp/bishin/index.html

I was born in Aichi Prefecture, have lived in Kanagawa, Okinawa, Kagawa, and Tokyo, and I am now living in Miyagi. When I was a student, I played soft-rubber ball tennis. I have been a fan of the professional baseball team, the Chunichi Dragons, but also support the Rakuten Eagles.

経歴 <Education> 1985-1989, Bachelor, Department of Agricultural Chemistry, The University of Tokyo, Tokyo, Japan; 1989-1991, Master, Department of Biotechnology, Graduate School of The University of Tokyo, Tokyo, Japan; 1995, Ph.D., Department of Biotechnology, Graduate School of The University of Tokyo, Tokyo, Japan.

<Employment> 1991-1996, Assistant Professor, Department of Agricultural Chemistry, The University of Tokyo, Tokyo, Japan; 1996-2000, Assistant Professor, Department of Biotechnology, Graduate School of The University of Tokyo, Tokyo, Japan; 2000-2001, Associate Professor, Institute of Genetic Ecology, Tohoku University, Sendai, Japan; 2001-present, Associate Professor, Department of Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.  
著書・論文 Nagata Y, Tabata M, Ohhata S, Tsuda M: Appearance and evolution of γ-hexachlorocyclohexane-degrading bacteria. In: Nojiri H, Tsuda M, Fukuda M, Kamagata Y (eds) Biodegradative Bacteria. Springer Verlag, Tokyo (2014)

Okai, M., J. Ohtsuka, L.F. Imai, T. Mase, R. Moriuchi, M. Tsuda, K. Nagata, Y. Nagata, and M. Tanokura. Crystal structure and site-directed mutagenesis analysis of haloalkane dehalogenase LinB from Sphingobium sp. MI1205. J. Bacteriol. 195: 2642-2651 (2013)

Ito, M., A. Ono, Y. Ohtsubo, M. Tsuda, and Y. Nagata. Cloning of γ-hexachlorocyclohexane dehydrochlorinase gene with its flanking regions from soil by activity-based screening techniques. European J. Soil Biology 52: 16-19 (2012)

Nagata, Y., S. Natsui, R. Endo, Y. Ohtsubo, N. Ichikawa, A. Ankai, A. Oguchi, S. Fukui, N. Fujita, and M. Tsuda. Genomic organization and genomic structural rearrangements of Sphingobium japonicum UT26, an archetypal gamma-hexachlorocyclohexane-degrading bacterium. Enzyme and Microbial Technology 49: 499-508 (2011)

Prokop, Z., Y. Sato, J. Brezovsky, T. Mozga, R. Chalooupkova, T. Koudelakova, P. Jerabek, V. Stepankova, R. Natsume, J. G.E. van Leeuwen, D. B. Janssen, J. Florian, Y. Nagata, T. Senda, and J. Damborsky. Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering. Angewandte Chemie. 49: 6111-6115 (2010)

Pavlova, M., M. Klvana, Z. Prokop, R. Chaloupkova, P. Banas, M. Otyepka, R. C. Wade, M. Tsuda, Y. Nagata, and J. Damborsky. Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate. Nature Chemical Biology 5: 727-733 (2009)

Fuchu, G., Y. Ohtsubo, M. Ito, R. Miyazaki, A. Ono, Y. Nagata, and M. Tsuda. Insertion sequence-based cassette PCR: cultivation-independent isolation of γ-hexachlorocyclohexane-degrading genes from soil DNA. Appl. Microbiol. Biotechnol. 79: 627-632 (2008)

Nagata, Y., R. Endo, M. Ito, Y. Ohtsubo and M. Tsuda. Aerobic degradation of lindane (γ-hexachlorocyclohexane) in bacteria and its biochemical and molecular basis. Appl. Microbiol. Biotechnol. 76: 741-752 (2007)
所属学会 Japan Society for Bioscience, Biotechnology and Agrochemistry; The Society for Biotechnology, Japan; Society of Genome Microbiology, Japan; Japanese Society of Microbial Ecology; Japan Society for Environmental Biotechnology; American Society for Microbiology.
担当講義 Microbial Genetics and Genomics (life science graduate students) Joint Lecture on Ecology (life science graduate students) Introduction to Life Science (all students)

最近の研究について

Biodegradation of environmental pollutants, e.g., halogenated pesticides and polyaromatic hydrocarbons. Evolution of bacterial genes and genomes. Protein engineering of dehalogenases. Bacterial ecology and metagenomics.

メッセージ

I am most interested in bacterial evolution in the environment.