Bioorganic Medicinal Chemistry

Focusing on the unique structures and biological activities of natural products, we are studying for total syntheses that are applicable to the preparation of their analogues. We elucidate structure activity relationships, not only to search for compounds with potent activity and high selectivity, but also to synthesize molecular probes using sites that are not involved in bioactivity toward the identification of their target molecules. We are also conducting research development of novel reactions forming unique structures in a large variation of compounds.