Molecular and Chemical Life Science :
Microbial Evolution and Function Research


Microbial Evolution and Function Research

Microbial Evolution and Function Research

Microbial evolution mechanisms and their application to new technologies

Research Overview

Some bacteria can consume artificially synthesized environmental pollutants. Previous studies have revealed the genes and enzymes that are used by such bacteria, and how they exert their pollutant degrading ability at the cellular level. However, little is known about the evolutionary "process" that these bacteria undergo, which appears to occur relatively quickly in a contaminated environment.
In our laboratory, we address the evolutionary mechanisms behind the emergence of such pollutant-metabolizing bacteria at the gene, enzyme, cell, genome, consortia, and environmental levels. Based on the findings, we aim to develop new technologies that use the previously unexplored microbial functions to clean up recalcitrant environmental pollutants. 
This laboratory was established in October 2016 with the support of the Institute for Fermentation, Osaka (IFO).

URLs http://www.ige.tohoku.ac.jp/bishin/index.html

Faculty Members

Professor NAGATA Yuji
  • Biodegradation of environmental pollutants
  • Evolution of bacterial genes and genomes
  • Protein engineering of dehalogenases
Lecturer YANO Hirokazu
  • Local diversification of bacterial species (animal pathogen)
  • Roles of genome methylation in bacteria
  • Persistence of mobile DNA in bacterial cell population
  • Why do microorganisms form a “community” ?
Assistant Professor KATO Hiromi
Assistant Professor SATO Yukari
  • Molecular basis analysis of transcription-associated proteins in human and biocatalyst enzymes from bacteria
  • Application of differential scanning fluorimetry to optimization of protein stabilization conditions