The Department of Immunobiology studies the immune system with a focus on the recognition mechanisms of NK and T cells in cancer, autoimmune diseases, and infectious diseases. We aim to elucidate the pathogenesis of these diseases using animal models and genetic recombination techniques, and to develop novel diagnostic and therapeutic approaches.
Research Overview
In our laboratory, Students from the Faculty of Science, Engineering, Pharmacy, Dentistry, and School of Medicine are enrolled, and it is also attractive to be able to interact with people from various backgrounds regardless of the field. In addition, our alumni are active in the world and can study in Japan and abroad.
Publications:
1. Yasaka K, et al. Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus. Arthritis research & therapy 25(1) 200-200, 2023.
2. Inamori K, et al. Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer. JCI insight 10.1172/jci.insight.137365, 2021.
3. Ueda T, et al. Formation of carbon-added anatase-rich TiO2 layers on titanium and their antibacterial properties in visible light. Dent Mater 37 (2), e37-e46, doi.org/10.1016/j.dental.2020.10.009, 2021
4. Kosuge M, et al. Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses. Scientific Reports 10.1038/s41598-020-74843-x, 2020.
5. Nakamura K, et al. Fratricide natural killer cells dressed with tumor-derived NKG2D ligand. Proc Natl Acad Sci USA 110 (23) : 9421-9426, 2013.
Award:
K. Nakamura The JSPS Ikushi Prize.
K. Ogasawara The MEXT Young Scientists' Prize.