GO TOP

Fields

Integrative Life Sciences :
Cooperative faculties

Research

Neuroanatomy

Neuroanatomy

The Department of Organ Anatomy focuses on the structural and developmental basis of human organs, while advancing research aimed at elucidating the molecular and cellular mechanisms that underlie physiological and pathological states. Our primary interest lies in the role of lipid metabolism in regulating the homeostasis of the immune and nervous systems, particularly in the context of energy metabolism, cell function, and differentiation.
 

Furthermore, we are elucidating how dysregulation of lipid metabolism contributes to the pathogenesis of neurodegenerative diseases, malignancies, and chronic inflammatory conditions. By integrating anatomical perspectives with contemporary life science approaches, we aim to both deepen basic biomedical research and foster the development of next-generation physician-scientists and biomedical researchers.
 

Research Overview

We investigate how lipid nutrition and membrane lipid remodeling influence neural plasticity, immune cell regulation, and intercellular communication within the tumor microenvironment. These studies employ a wide array of techniques, including genetically engineered mouse models, primary cell cultures, omics-based analyses, and in vivo imaging.
URLs https://organ-anatomy.med.tohoku.ac.jp/

Faculty Members

Professor OWADA Yuji
More
Mechanisms linking developmental nutritional stress and disease.