Professor (Cross Appointment) YONEKURA Koji
| Campus | Katahira campus |
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| Laboratory |
Structural Mechanism Research and Development
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| koji.yonekura.a5＠tohoku.ac.jp | |
| Website | https://www2.tagen.tohoku.ac.jp/lab/yonekura/ |
| Career |
1997 Graduate School of Biosciences, Tokyo Institute of Technology Ph. D.
1997 Research Associate, International Institute for Advanced Research,
Matsushita Electric Industrial Co., Ltd. 1997 - 2001 Researcher, Group Leader, JST ERATO Protonic Nano Machine Project
2002 - 2005 Assistant Professor, Graduate School of Frontier Biosciences, Osaka University
2004 - 2008 Keck Fellow, University California San Francisco
2008 - 2018 Associate Chief Scientist, Chief Scientist, Biostructural Mechanism Laboratory, RIKEN SPring-8 Center
2018 - Group Director, as above
2018 - Unit Leader, Advanced Electron Microscope Development Unit, as above
2020 - Professor, IMRAM, Tohoku University (cross appointment)
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| Selected Publications |
1. Yonekura K., Maki-Yonekura S., Naitow H., Hamaguchi T., Takaba K. Machine learning-based real-time object locator / evaluator for cryo-EM data collection. Commun. Biol. 2021, 4, 1044.
2. Maki-Yonekura S., Hamaguchi T., Naitow H., Takaba K., Yonekura K. Advances in cryo-EM and ED with a cold-field emission beam and energy filtration: - refinements of the CRYO ARM 300 system in RIKEN SPring-8 Center –. Microscopy 2021, 70, 232–240.
3. Takaba K., Maki-Yonekura S., Inoue S., Hasegawa T., Yonekura K. Protein and organic-molecular crystallography with 300kV electrons on a direct electron detector. Front. Mol. Biosci. 2021, 7, 612226.
4. Naitow H., Hamaguchi T., Maki-Yonekura S., Yoshikawa N., Isogai M., Yonekura K. Apple latent spherical virus structure with stable capsid frame supports quasi-stable protrusions expediting genome release. Commun. Biol. 2020, 3, 488.
5. Hamaguchi T., Maki-Yonekura S., Naitow H., Matsuura Y., Ishikawa T., Yonekura K. A new cryo-EM system for single particle analysis. J. Struct. Biol. 2019, 207, 40-48.
6. Yonekura K., Ishikawa T, Maki-Yonekura S. A new cryo-EM system for electron 3D crystallography. J. Structl. Biol. 2019, 206, 243-253.
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| Activities in Academic Societies |
The Biophysical Society of Japan; The Japanese Society of Microscopy
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| Teaching |
Advanced molecular and chemical biology seminar III (Multilevel biomolecular structure and dynamics)
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Recent Activities
Our cryo-EM analyses have revealed hydrogen properties and charges in protein and organic molecules. To realize and utilize such new possibilities, we have developed related technologies including AI data collection. We also use synchrotron radiation and computational science to elucidate detailed structural mechanisms of those molecules.