In graduate school, we worked on the elucidation of epigenetic mechanisms for the regulation of gene expression in budding yeast. Currently, I am attracted to study of the germ cells responsible for intergenerational information inheritance. I am interested in how the information possessed by germ cells is changed or inherited through dynamic phenomena such as germ-cell differentiation, fertilization, and ontogeny.
Germ Cell Development
|Activities in Academic Societies||
The Molecular Biology Society of Japan, Japanese Society of Developmental Biologists
I started researching the metabolic regulation of germline development. It is becoming clear that metabolism is indispensable for maintaining life in many organisms and cell types and its regulation affects the determination of cell fates. Recent research topics are how the metabolic activity is controlled during germline development, and how the metabolic regulation of germ cells affects their reproductive functions for inheriting genetic and epigenetic information to the next generation.
Metabolic analysis in a small number of cells like germ cells is almost unprecedented, so I am tacking on challenging experiments everyday.