Molecular and Chemical Life Science :
Multilevel Biomolecular Structure and Dynamics


Assistant Professor OIKAWA Hiroyuki
Campus Katahira campus
Laboratory Molecular Analysis of Biological Functions
Tel +81-22-217-5843
E-mail hiroyuki.oikawa.d1@tohoku.ac.jp
Website http://www2.tagen.tohoku.ac.jp/lab/takahashi-s/

I have liked to build new apparatuses since I was a student. Even now I am developing a device for detecting single molecules using a combination of the optical measurement and the automated data analysis.


Graduated from Department of Physics, Tokyo Institute of Technology; completed master’s course, Department of Physics, Graduate School of Science and Engineering, Tokyo Institute of Technology.
Completed doctoral course and acquired Doctor of Science, Department of Physics, Graduate School of Science and Engineering, Tokyo Institute of Technology.
Achieved current position after serving as a project researcher, Institute for Protein Research, Osaka University, and a as a postdoctoral fellow, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University.

Selected Publications

Hiroyuki Oikawa, Kiyoto Kamagata ,Munehito Arai, and Satoshi Takahashi “Complexity of the Folding Transition of the B domain of Protein A Revealed by the High-Speed Tracking of Single-Molecule Fluorescence Time Series” J. Phys. Chem. B, 119, 6081-6091 (2015)

Hiroyuki Oikawa, Yuta Suzuki, Masataka Saito, Kiyoto Kamagata, Munehiro Arai, and Satoshi Takahashi “Microsecond dynamics of an unfolded protein by a line confocal tracking of single molecule fluorescence” Sci. Rep. 3, 2151, (2013)

Daisuke Uchiyama, Hiroyuki Oikawa, Kohei Otomo, Mamoru Nango, Takehisa Dewa, Satoru Fujiyoshi, and Michio Matsushita “Reconstitution of bacterial photosynthetic unit in a lipid bilayer studied by single-molecule spectroscopy at 5 K”, Phys. Chem. Chem. Phys., 13, 11615-11619 (2011)

Hiroyuki Oikawa, Satoru Fujiyoshi, Takehisa Dewa, Mamoru Nango, and Michio Matsushita “How Deep Is the Potential Well Confining a Protein in a Specific Conformation? A Single-Molecule Study on Temperature Dependence of Conformational Change between 5 and 18 K. “ J. Am. Chem. Soc., 130, 4580-4581. (2008)

Activities in Academic Societies

The Biophysical Society of Japan, Protein Science Society of Japan, Japan Society for Molecular Science

Recent Activities

Microsecond-resolved tracking of single-molecule dynamics of protein folding.

Message to Students

Let us observe an individual character of each single biomolecule using the unique methods.