GO TOP

Field

Integrative Life Sciences :
Cellular Network

Research

Assistant Professor MUKAI Kojiro
Campus Aobayama campus
Laboratory Organelle Pathophysiology
Tel +81-22-795-6678
E-mail kojiro.mukai.d1@tohoku.ac.jp
Career
2010
B.Sc., Graduate School of Pharmaceutical Sciences, the University of Tokyo
 
2015
Ph.D., Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, the University of Tokyo
 
2015-2018
Assistant professor, Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, the University of Tokyo
 
2018-current
Assistant professor, Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University
Selected Publications
  1. Hansen, A. L., Buchan, G. J., Rühl, M., Mukai, K., Salvatore, S. R., Ogawa, E., Andersen, S. D., Iversen, M. B., Thielke, A. L., Gunderstofte, C., Motwani, M., Møller, C. T., Jakobsen, A. S., Fitzgerald, K. A., Roos, J., Lin, R., Maier, T. J., Goldbach-Mansky, R., Miner, C. A., Qian, W., Miner, J. J., Rigby, R. E., Rehwinkel, J., Jakobsen, M. R., Arai, H., Taguchi, T., Schopfer, F. J., Olagnier, D., and Holm, C. K. (2018). Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling. Proc Natl Acad Sci U S A 115, E7768-E7775
  2. Ogawa, E.*, Mukai, K.*, Saito, K., Arai, H., and Taguchi, T. (2018). The binding of TBK1 to STING requires exocytic membrane traffic from the ER. Biochem Biophys Res Commun 503, 138-145.(*equal contribution)
  3. Takahashi, M., Mohan, P., Mukai, K., Takeda, Y., Matsumoto, T., Matsumura, K., Takakura, M., Arai, H., Taguchi, T., and Maenosono, S. (2017). Magnetic Separation of Autophagosomes from Mammalian Cells Using Magnetic–Plasmonic Hybrid Nanobeads. ACS Omega 2, 4929-4937.
  4. Matsudaira, T.*, Mukai, K.*, Noguchi, T., Hasegawa, J., Hatta, T., Iemura, S., Natsume, T., Miyamura, N., Nishina, H., Nakayama, J., Semba, K., Tomita, T., Murata, S., Arai, H., and Taguchi, T. (2017). Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells. Nat Commun 8, 651. (*equal contribution)
  5. Mukai, K., Konno, H., Akiba, T., Uemura, T., Waguri, S., Kobayashi, T., Barber, G. N., Arai, H., and Taguchi, T. (2016). Activation of STING requires palmitoylation at the Golgi. Nat Commun 7, 11932.
  6. Lee, S., Uchida, Y., Wang, J., Matsudaira, T., Nakagawa, T., Kishimoto, T., Mukai, K., Inaba, T., Kobayashi, T., Molday, R. S., Taguchi, T., and Arai, H. (2015). Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. EMBO J 34, 669-688.
  7. Uchida, Y., Hasegawa, J., Chinnapen, D., Inoue, T., Okazaki, S., Kato, R., Wakatsuki, S., Misaki, R., Koike, M., Uchiyama, Y., Iemura, S., Natsume, T., Kuwahara, R., Nakagawa, T., Nishikawa, K., Mukai, K., Miyoshi, E., Taniguchi, N., Sheff, D., Lencer, W. I., Taguchi, T., and Arai, H. (2011). Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes. Proc Natl Acad Sci U S A 108, 15846-15851.
     
Activities in Academic Societies
Japanese Biochemical Society, Japan Society for Cell Biology, The Japanese Conference on the biochemistry of lipids