Molecular and Chemical Life Science :
Chemical Biology


Assistant Professor CHIBA Shuhei
Campus Aobayama campus
Laboratory Molecular and Cellular Biology
Tel +81-22-795-6593
Website https://konagata.wixsite.com/ohashi-lab
Selected Publications
  1. *Katoh Y, *Chiba S, Nakayama K. Practical method for superresolution imaging of primary cilia and centrioles by expansion microscopy using an amplibody for fluorescence signal amplification. Mol Biol Cell. 2020 Sep 15;31(20):2195-2206. doi: 10.1091/mbc.E20-04-0250. Epub 2020 Jul 29. PubMed PMID: 32726175; PubMed Central PMCID: PMC7550703.  (*equally contribution)
  2. *Kashihara H, *†Chiba S, Kanno SI, Suzuki K, Yano T, †Tsukita S. Cep128 associates with Odf2 to form the subdistal appendage of the centriole. Genes Cells. 2019 Mar;24(3):231-243. doi: 10.1111/gtc.12668. Epub 2019 Feb 18. PubMed PMID: 30623524. (*: equally contribution, †: co-corresponding)
  3. Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017 Jan 12;168(1-2):264-279.e15. doi: 10.1016/j.cell.2016.12.032. Epub 2017 Jan 12. PubMed PMID: 28086093; PubMed Central PMCID: PMC5660509. 
  4. *Oda T, *Chiba S, *Nagai T, Mizuno K. Binding to Cep164, but not EB1, is essential for centriolar localization of TTBK2 and its function in ciliogenesis. Genes Cells. 2014 Dec;19(12):927-40. doi: 10.1111/gtc.12191. Epub 2014 Oct 9. PubMed PMID: 25297623. (*equally contribution)
  5. Su S, Phua SC, DeRose R, Chiba S, Narita K, Kalugin PN, Katada T, Kontani K, Takeda S, Inoue T. Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia. Nat Methods. 2013 Nov;10(11):1105-7. doi: 10.1038/nmeth.2647. Epub 2013 Sep 22. PubMed PMID: 24056873; PubMed Central PMCID: PMC3860264. 
  6. Chiba S, Amagai Y, Homma Y, Fukuda M, Mizuno K. NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15. EMBO J. 2013 Mar 20;32(6):874-85. doi: 10.1038/emboj.2013.32. Epub 2013 Feb 22. PubMed PMID: 23435566; PubMed Central PMCID: PMC3604723.  
  7. Chiba S, Ikeda M, Katsunuma K, Ohashi K, Mizuno K. MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes. Curr Biol. 2009 Apr 28;19(8):675-81. doi: 10.1016/j.cub.2009.02.054. Epub 2009 Mar 26. PubMed PMID: 19327996.