GO TOP

Field

Integrative Life Sciences :
Cooperative faculties

Research

Professor TAKAHASHI Mayu
Campus Seiryo campus
Laboratory Systems Neurophysiology
Tel +81-22-717-8071
E-mail mayu.takahashi.a5@tohoku.ac.jp
Website https://www.neurophysiology.med.tohoku.ac.jp/
Career
2008.03    Graduated MD-PhD Course, Received PhD, Tokyo Medical and Dental University
2009.03    Graduated Medical School and received MD, Tokyo Medical and Dental University
2009.04 Internship in University Hospital, Tokyo Medical and Dental University (Japan)
2010.04    Assistant Professor, Dept. of Systems Neurophysiology 
    Graduate School of Medicine, Tokyo Medical and Dental University
2021.04 Junior Associate Professor (ditto) 
2024.04    Associate Professor, Dept. of Neuroanatomy and Cellular Neurobiology
        Graduate School of Medicine, Tokyo Medical and Dental University
2024.04    Associate Professor, Dept. of Physiology, 
Graduate School of Medicine, The University of Tokyo
2024.10 Professor, Dept. of Physiology, Graduate School of Medicine, Tohoku University
 
Selected Publications
  1. Takahashi M, Sugiuchi Y, Shinoda Y. Brainstem neural circuits for triggering vertical saccades and fixation. J. Neuroscience 44(1): e1657232023, 2024. 
  2. Takahashi M, Sugiuchi Y, Na J, Shinoda Y. Brainstem neural circuits triggering saccades and fixation. J. Neuroscience 42: 789-803, 2022. 
  3. Takahashi M, Sugiuchi Y, Shinoda Y. Neural substrates for generation of oblique saccades. Equilibrium Research 81: 67-78, 2022.  
  4. Takahashi M, Shinoda Y. Neural circuits of inputs and outputs of the cerebellar cortex and nuclei. Neuroscience 462: 70-88, 2021.
  5. Takahashi M, Shinoda Y. Brain stem neural circuits for horizontal and vertical saccade systems and their frame of reference. Neuroscience 392: 281-328, 2018.
  6. Takahashi M, Sugiuchi Y, Shinoda Y. Convergent synaptic inputs from the caudal fastigial nucleus and the superior colliculus onto pontine and pontomedullary reticulospinal neurons. J. Neurophysiology 111: 849-867, 2014. 
  7. Sugiuchi Y, Takahashi M, Shinoda Y. Input-output organization of inhibitory neurons in the interstitial nucleus of Cajal projecting to the contralateral trochlear and oculomotor nucleus. J. Neurophysiology 110: 640-657, 2013. 
  8. Takahashi M, Sugiuchi Y, Shinoda Y. Topographic organization of excitatory and inhibitory commissural connections in the superior colliculi and their functional roles in saccade generation. J. Neurophysiology 104: 3146-3167, 2010.  
  9. Takahashi M, Sugiuchi Y, Shinoda Y. Commissural mirror- symmetric excitation and reciprocal inhibition between the two superior colliculi and their roles in vertical and horizontal eye movements. J. Neurophysiology 98:2664-2682, 2007. 
  10. Takahashi M, Sugiuchi Y, Izawa Y, Shinoda Y. Commissural excitation, and inhibition by the superior colliculus in tectoreticular neurons projecting to omnipause neuron and inhibitory burst neuron regions. J. Neurophysiology 94:1707-1726, 2005. 
     
Activities in Academic Societies
  1. The Society for Neuroscience 
  2. The International Union of Physiological Sciences 
  3. The Barany Society 
  4. The Society of the Neural Control of Movement 
  5. The Japan Neuroscience Society
  6. The Physiological Society of Japan
  7. Japanese Society for Cerebellum and its Disorders
  8. The Japanese Neuro-Ophthalmology Society
  9. The Japan Society for Equilibrium Research

Recent Activities

    Why do we move our eyes? In daily life, our eyes move three to four times every second, yet the neural and cognitive processes that lead to the selection of where we will look next, and then execute the appropriate eye movement, are entirely unconscious and automatic. We, like other animals, move our eyes, heads, and bodies in the world to direct our sensory organs to targets in the world that our brains deem important. Much like walking or reaching to pick up a cup, we take this amazing ability for granted – until something causes it to break.
    Our primary focus is on the mechanisms, representations, and transformations that make the abovementioned function possible. We investigate these questions using intricate behavioral, cognitive, and neurophysiological studies applied to appropriate animal species or humans as necessary. This question – of what attention is and how it is implemented and why it works – is of great interest not only from the point of view of understanding the anatomy and physiology, but also for its application in medicine and artificial intelligence. There is also a strong expectation that understanding the principles of the “simpler” visuo-ocular-motor control system will give us hints into how the brain organizes more “complex” perceptual and motor control systems.