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研究分野

脳生命統御科学専攻 :
細胞ネットワーク講座

研究

Glen Barber

客員教授 Glen Barber
キャンパス 青葉山 キャンパス
所属研究室 細胞小器官疾患学
経歴
1989年 Ph.D. (London University)
1996 – 1998年 Assistant Professor, Department of Microbiology and Immunology, Emory University
1999 – 2004年 Associate Professor, Department of Microbiology and Immunology, University of Miami Miller School of Medicine (UMMSOM)
2004 – 2024年 Professor, Department of Microbiology and Immunology, UMMSOM
2024年 – Director of the Center for Innate Immunity and Inflammation, Pelotonia Institute for Immuno-Oncology, The Ohio State University
 
著書・論文
Balachandran, S., Thomas, E. & Barber, G. N. A FADD-dependent innate immune mechanism in mammalian cells. Nature 432, 401–405 (2004).
 
Ishikawa, H., Ma, Z. & Barber, G. N. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461, 788–792 (2009).
 
Ishikawa, H. & Barber, G. N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455, 674–678 (2008).
 
Mukai, K. et al. Homeostatic regulation of STING by retrograde membrane traffic to the ER. Nat Commun 12, 61 (2021).
 
Kuchitsu, Y. et al. STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes. Nat. Cell Biol. 25, 453–466 (2023).