【開催日時・Date】
2024.9.13(Fri) 16:00～17:30
【講師・Speaker】
Dr. Andre Pires da Silva
2024.9.13(Fri) 16:00～17:30
【講師・Speaker】
Dr. Andre Pires da Silva
School of Life Sciences, University of Warwick, UK
【会場・Venue】ハイブリッド開催（Hybrid）
片平・生命科学プロジェクト研究棟講義室AB
Life Sciences Project Research Laboratory, Lecture hall
【事前登録・Pre-registration】
Zoom link
https://zoom.us/meeting/register/tJwpcu2upjotHdH6Efme17Rem5kDJO3AaQoP
【使用言語・Language】
English
【題目・Title】
Evolution of sex determination and sex-ratio bias
【要旨・Abstract】
Sex-determining mechanisms are characterized by their rapid evolution and diversity even among populations of the same species. We focus on the study of sex determination in free-living nematodes of the genus Auanema, revealing the mechanisms that control the development of males, females, and hermaphrodites. Intriguing findings emerged from crossing different sexual morphs: matings between hermaphrodites and males yield only male progeny, while crosses between males and females produce exclusively non-male offspring. Interestingly, hermaphrodites emerge in response to specific social cues sensed by the maternal generation. These results can be attributed to unusual genetic phenomena, including non-Mendelian inheritance, chromatin diminution, inverted meiosis, and the occurrence of transgression. Our study not only unravels the complexities of sex determination in Auanema nematodes but also contributes to a broader understanding of genetic and evolutionary dynamics in developmental mechanisms.
Sex-determining mechanisms are characterized by their rapid evolution and diversity even among populations of the same species. We focus on the study of sex determination in free-living nematodes of the genus Auanema, revealing the mechanisms that control the development of males, females, and hermaphrodites. Intriguing findings emerged from crossing different sexual morphs: matings between hermaphrodites and males yield only male progeny, while crosses between males and females produce exclusively non-male offspring. Interestingly, hermaphrodites emerge in response to specific social cues sensed by the maternal generation. These results can be attributed to unusual genetic phenomena, including non-Mendelian inheritance, chromatin diminution, inverted meiosis, and the occurrence of transgression. Our study not only unravels the complexities of sex determination in Auanema nematodes but also contributes to a broader understanding of genetic and evolutionary dynamics in developmental mechanisms.
Reference:
DC.Shakes, et.al., Nature commun. 2 (1), 157 (2011)
J. Chaudhuri, et.al., Scientific Reports 5 (1), 17676 (2015)
N. Kanzaki, et.al., Scientific reports 7 (1), 11135 (2017)
S. Tandonnet, et.al.,Curr. Biol., 28, 93-99 (2018)
T. Al-Yazeedi, et.al., Genetics, 222, iyae159 (2022)
T. Al-Yazeedi, et.al., Genetics, 227, iyae032 (2024)
DC.Shakes, et.al., Nature commun. 2 (1), 157 (2011)
J. Chaudhuri, et.al., Scientific Reports 5 (1), 17676 (2015)
N. Kanzaki, et.al., Scientific reports 7 (1), 11135 (2017)
S. Tandonnet, et.al.,Curr. Biol., 28, 93-99 (2018)
T. Al-Yazeedi, et.al., Genetics, 222, iyae159 (2022)
T. Al-Yazeedi, et.al., Genetics, 227, iyae032 (2024)
Contact
生命科学研究科 発生ダイナミクス分野
Grad. Sch. of Life Sciences, Developmental Dynamics
杉本亜砂子
Asako Sugimoto
E-mail：asako.sugimoto.d1(at)tohoku.ac.jp
生命科学研究科 発生ダイナミクス分野
Grad. Sch. of Life Sciences, Developmental Dynamics
杉本亜砂子
Asako Sugimoto
E-mail：asako.sugimoto.d1(at)tohoku.ac.jp